screening drug, post entry restriction factor and host dependency factor the present invention relates to a kind of novel hepatitis type B virus (HBV) and/or Hepatitis D virus (HDV) receptor and its in exploitation cell, cell line and non-human animal some couples of HBV and/or HDV ...
该研究探索了功能失调的HBV特异性CD8 + T细胞的行为和潜在的治疗靶点,发现肝细胞启动可诱导功能失调的CD8+T细胞中的关键共信号受体,长时间的HBV抗原刺激产生一个自我更新的、长寿命的、异质性的T细胞库,在慢性HBV感染中, 激活4-1BB(一种T细胞共刺激免疫检查点分子) 显示出最高潜力的恢复功能受损的CD8+T细胞。 这...
PATIENT'S SERUM]]>Chu Hoàng HàĐại học Quốc gia Hà Nội
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Blockade of TIGIT pathway mediates liver inflammation in HBV-transgenic miceBackground:Chronic hepatitis B virus(HBV)infection is characterized by continuing liver in To investigate the mechanisms which co-inhibitory pathway mediates liver immune tolerance toward HBV infection in HBV carrier mice and to ...
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