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此外,FGF-23亦可通过上调肾脏Na+-Cl-同向转运子、促进钠离子吸收等导致容量负荷增加、高血压和LVH[124],已有研究证实,FGF-23与心力衰竭患者住院率及死亡率相关 [125]。(2)维生素D缺乏:维生素D可通过抑制肾素-血管紧张素-醛固酮系统(renin-angiotensin-aldosteronesystem,RAAS)、抗炎、抗氧化[126]、抑制钙调磷酸酶...
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