Treatment There is presently no licensed targeted therapy for acute CHIKV infection. Treatment is primarily supportive care and includes the use of analgesic and anti-inflammatory medication, rehydration, and rest. However, research to identify potential new antiviral therapies, or repurposing of existing...
which are essential in symptomatic treatment for individuals infected with the chikungunya virus [159]. Despite having a low risk of mortality, the chikungunya virus can be lethal for children and the elderly [160,161]. The current CMGs
There is currently no specific treatment for the infection, and the main form of prevention is vector control, similar to the dengue and zika viruses. This includes regularly emptying and cleaning containers with stagnant water, such as plant pots, buckets, tires and plastic bottles. ...
Three vaccine products have been given fast track designation by US Food and Drug Administration (FDA) to expedite review and facilitate the development of a vaccine to prevent a serious or life-threatening condition and fill an unmet medical need. Similarly, one vaccine has been given PRIME (...
In the absence of preventative treatment, until now the only way to protect against infection was to avoid getting bitten. The vaccine is injected in one dose and contains a live, weakened version of the chikungunya virus, as is standard with other vaccines. ...
There are two VLP vaccines for other diseases approved by the Food and Drug Administration: one for hepatitis B and one for human papillomavirus. This study marks the first time that scientists have used VLPs in avaccineto protect against chikungunya virus, which is in the genus Alphavirus. Th...
2D structures of several natural product drugs used in the treatment of cancer (paclitaxel, a), hypertension (reserpine, b), malaria (artemisinin, c). Compound d [10] is one of the natural product which displayed inhibitory activity against neglected tropical disease, dengue virus infection Full...
The invention concerns a new medicinal product for the treatment of chikungunya, i.e a concentrate of chikungunya-specific immunoglobulins, as well as its process of preparation.</d
structural proteins, in particular CHIKV-Virus Like Particles expressing CHIKV structural proteins, in particular CHIKV-CE3E26KE1 VLPs or the composition according to the invention, for use in the treatment or the prevention of an infection by Chikungunya virus in a subject, in particular in a...
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