Kraut J. 1971. Chymotrypsinogen: X-ray structure. In: The Enzymes, Vol. 3. Boyer PD, editor. New York: Academic Press; pp. 165–183.Chymotrypsinogen: x-ray structure - Kraut () Citation Context ...es are only a few residues long (14) and therefore removal of the peptide during ...
A model structure is assumed for type D crystals of chymotrypsinogen in which the molecule is represented by a 21 sphere, and for which the calculated X-ray intensities out to a Bragg spacing of 18 give satisfactory agreement with observation. Phases deduced for this model are used together wit...
Aggregate structureAggregation of chymotrypsinogen results in amyloid polymers at acidic pH.Removal of the C191-C220 disulfide does not change the measurable secondary or tertiary structure by CD or fluorescence.Removing the C191-C220 disulfide lowers the nucleation barrier, and shifts the nucleus size...
During the work of site\|directed mutagenesis at disulfide bond Cys206\|Cys210 of prochymosin,it was found that the corresponding template sequence had the potential to form a loop\|stem structure with free energy of -16 1 kcal/mol,which prevent the template from pairing with primer and,in...
Based on chymase Aa sequence,the secondary structure and B-cell epitope of human mast cell chymase were predicted by methods of Hopp & Woods hydrophilicity,antigenicity(Welling) and accessibility(Janin) parameters. 根据肥大细胞Chymase的氨基酸序列,借助ProScale服务器,采用Hopp&Woods的亲水性方案、Janin可...
Structure of chymotrypsinogen B compared with chymotrypsinogen A and trypsinogen. Nature. 1968 Apr 27; 218 (5139):343–346.L. B. Smillie, A. Furka, N. Nagabhushan, K. J. Stevenson, C. O. Parkes, "Structure of chymotrypsinogen B compared with chymotrypsinogen A and trypsinogen," Nature, ...
The model showed high similarity to the X-ray crystal structure of bovine chymotrypsinogen A, thus, demonstrated that the three-dimensional structure is more conserved in evolution than protein sequences.doi:10.1007/BF01876843De-Xing HouYifei Wang...
— The time‐resolved tryptophyl fluorescence of α‐chymotrypsinogen A and α‐chymotrypsin in the crystalline state and in buffer solution at room temperature was analyzed globally. Tripleexponential decay functions are necessary to adequately describe the tryptophyl fluorescence decay surfaces of the ...
作者: EL Smith,DM Brown,M Laskowski 展开 摘要: PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. 展开 关键词: CHYMO...
Non-native aggregation is the process in which protein monomers self-assemble into aggregates in which the constituent monomers have significantly non-native structure. These aggregates range in size and morphology, but are commonly rich in β-sheet content. Non-native aggregates and their upstream...