CNS depression is the commonest effect in poisoned patients in casualty. In the last 20 years antidotes have been found to treat poisoning by two of the most frequent toxic agents causing toxic coma, opiates and benzodiazepines.Naloxone and flumazenil can be considered antidotes in the most ...
Analgesia(inability to feel pain), Sedation, Respiratory depression, Constipation, nausea, cough reflex. Paitents that would be considered "opioid naive" could develop what problem when placed on a strong or high dose. Respiratory Depression and Constipation ...
Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression. Neuron 57: 203–209. Vanda Pharmaceuticals (2008). Vanda Pharmaceuticals announce receipt of not approvable letter from FDA for iloperidone. http://phx.corporate-ir.net/ phoenix.zhtml?c ¼ ...
These include the long-term potentiation (LTP) and long-term depression (LTD) of synaptic strength, each of which is induced by highly specific patterns of activity of glutamatergic afferents139. When mGluR5 is activated by glutamate that is released from the terminals of afferents that fire ...
-END is involved in anti-stress mechanisms and well-being. Perhaps the involvement of β-END in depression gives this mind-state a considerable, but undesirable, degree of stability. In that case, the stability of a depression has to be considered as an unpleasant side effect. A discussion ...
The most common (=10%) adverse events involving Optune in combination with temozolomide were low blood platelet count, nausea, constipation, vomiting, fatigue, scalp irritation from device use, headache, convulsions, and depression. The most...
10. A method of treating the positive and negative symptoms of schizophrenia, other psychoses, anxiety disorders, depression, aggression, side effects induced by conventional antipsychotic agents, migraine, cognitive disorders, ADHD and in the improvement of sleep comprising administration of a therapeutica...
STAR*D Abstract The STAR*D (Sequenced Treatment Alternatives to Relieve Depression) study used a series of sequenced, randomized treatment trials following a first and, if needed, subsequent treatment steps to define the tolerability and effectiveness of various options in both acute and longer term...
although this protein is of primary interest to epilepsy, it may also be of use in neurodegenerative diseases where synaptic loss is associated with cognitive impairment [212,213] and other diseases, such as schizophrenia and depression, where regional synaptic alterations have been implicated [214,...
Sertraline, whose chemical name (1S,4S)-cis 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine, is approved for the treatment of depression by the United States Food and Drug Administration, and is available under the trade name ZOLOFT® (Pfizer Inc., NY, N.Y., US...