Although in hemizygous males the symptomatology is more severe and the disease has a higher incidence, females can also be affected particularly at later ages and with an overall lower frequency in symptoms manifestation, with the exception of cerebrovascular phenotypes which are as frequent as in ...
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The order of presentation reflects the impact of the organ or system on the morbidity and premature mortality associated with Fabry disease. Thus, kidney, heart, and cerebrovascular involvement are discussed first, fol- lowed by pain, sweat function, quality of life, and gastrointestinal symptoms. ...
When Fabry disease is “treated” in the above method, this means that one or more symptoms of Fabry disease are ameliorated. It does not mean that the symptoms of Fabry disease are completely remedied so that they are no longer present in the patient, although in some methods, this may b...
(n = 8). Reduced QoL was reported in patients with FD compared with healthy populations across multiple domains, including pain, physical functioning, and depressive symptoms. Multiple variables—including sex, age, disease severity, and treatment status—impacted QoL. Of the 711 records ...