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[1] Five Prime Announces Bemarituzumab Plus Chemotherapy Demonstrates Significant Progression-Free and Overall Survival Benefit Compared to Placebo Plus Chemotherapy in Front-Line Advanced Gastric and Gastroesophageal Junction Cancer. Retrieved November 10, 2020, from https://www.businesswire.com/news/hom...
《cancer research》 被引量: 616 发表: 2001年 vegfr2和c—cbl在胃癌组织中的表达及其临床意义 目的:探讨vegfr2和c-cbl在胃癌组织中的表达及其临床意义.方法:构建胃癌组织芯片,应用免疫组化的方法,检测两种蛋白的表达情况.结果:vegfr2和c-cbl在胃癌组织中的阳性表... 李琳琳 , 刘云鹏 , 侯柯佐 ,...- 《...
参考资料: https://www.cancernetwork.com/view/fda-grants-breakthrough-therapy-designation-to-bemarituzumab-for-frontline-fgfr2b-gastric-gej-cancers
The gene amplification of the FGFRs in formalin-fixed, paraffin-embedded (FFPE) gastric cancer tissues was determined by a real-time PCR-based copy number assay and fluorescence in situ hybridisation (FISH). RESULTS: FGFR2 amplification confers hypersensitivity to FGFR inhibitor in gastric cancer ...
(HER-2/neu)=3.153).Positive expressions might herald a short survival time,and the positive expression of HER-2/neu might be even more predictive.Conclusion Determination of the expression of EGFR and HER-2/neu in gastric cancer tissues may be helpful to determine the prognosis,guide the ...
Bemarituzumab for FGFR2b-Positive Gastric Cancer bemarituzumab治疗FGFR2b阳性胃癌 评论作者:David H. Ilson, MD, PhD bemarituzumab是阻断FGFR2b的单克隆抗体,在2期研究中对FGFR2b过表达或FGFR2基因扩增的患者有效。 在纳入食管胃腺癌患者的临...