Myoblast cultures Transgenic GFP+ and WT (C57.B6) mouse myoblasts were cultured in growth medium: Ham’s F10, 20% Bovine Growth Serum and 5 ng/ml bFGF on\(1\,\mu \hbox {g}/\hbox {cm}^2\)Matrigel. Cells were washed and detached with PBS (three 37C) and were pelleted by centrif...
- 《Journal of Molecular & Cellular Cardiology》 被引量: 34发表: 1987年 Studies on the effect of chronic L-triiodothyronine (T3) treatment on brain Na+,K+-ATPase activity in the mature rat Mature rats were dosed with T3 by different routes and dose-levels at either 0.1 mg/kg for 14 ...
we thus fed 8-week-old KO mice and WT littermates with HFD for 16 weeks. Remarkably, the KO mice were significantly protected from HFD-induced obesity, as evidenced by the significantly lower body weight (Fig.4A, B) along with a marked reduction of the WAT mass (Fig.4C, D) and...
Herein we hypothesize that ATP-sensitive potassium (K-ATP) channels as molecular sensors of cellular metabolism may mediate the cardioprotective effects of resveratrol. Kir6.2 knockout, Kir6.1 heterozygous and wild-type (WT) mice were subjected to ischemia/reperfusion injury and were injected with ...
然后通过CUT&Tag来分析H3K36me3在野生型(WT)和Setd2 KO细胞中的分布。结果显示正如之前报道的,在WT细胞中通过NCBI RefSeq鉴定的基因中,H3K36me3水平显示从转录起始位点(TSS)到转录终止位点(TES)的连续增加。当Setd2被敲除时,基因体区域的H3K36me3富集基本上被消除。但是作者还发现在WT和Setd2 KO...
Skip to main contentSkip to article Journals & Books Help Search My account
In summary, our results suggest subtle changes in the molecular motions of class II molecules correlate with a significant impact on class II function. Molecules active in antigen presentation exhibit more restricted motion in the membrane, and thus presumably more extensive intermolecular interactions, ...
It contains Gly25-Thr305(HLA-A*11:01),Ile21-Met119(B2M) and VVVGAGGVGK peptide.[Accession | AAV53343.1(HLA-A*11:01)&P61769(B2M)&VVVGAGGVGK]分子量大小(Molecular Weight) The protein has a predicted MW of 50.30 kDa. Due to glycosylation, the protein migrates to 52-62 kDa based ...
Ye, B.; Kroboth, S.L.; Pu, J.L.; Sims, J.J.; Aggarwal, N.T.; McNally, E.M.; Makielski, J.C.; Shi, N.Q. Molecular identification and functional characterization of a mitochondrial sulfonylurea receptor 2 splice variant generated by intraexonic splicing.Circ. Res.2009,105, 1083–...
Because the K63-linked polyubiquitination is known to play an important role in protein-protein interaction, TRAF6-mediated ATG9A ubiquitination may serve as a molecular platform to facilitate VPS34-UVRAG complex assembly, autophagosome maturation, and endocytic trafficking under oxidative stress conditions...